Game Time: 12:35 pm ET, Thursday, April 28, 2022
Venue: Great American Ball Park, Cincinnati, OH
Where to Watch: BSOH
Opening Odds at USA Sportsbooks
DraftKings: Moneyline odds: Padres -125, Reds +105; Over/Under: 8 runs
Bet365: Moneyline odds: Padres -125, Reds +105; Over/Under: 8 runs
BetMGM: Moneyline odds: Padres -125, Reds +105; Over/Under: 8 runs
Season Record
San Diego Padres: 11-7 (3rd place, NL West)
Cincinnati Reds: 3-14 (5th place, NL Central)
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San Diego Padres vs Cincinnati Reds Preview and Analysis
Recent Form
San Diego Padres: 6-4 last 10
Cincinnati Reds: 1-9 last 10
San Diego Padres Analysis
The Padres are coming into this game with a 11-7 record overall and they are 5-3 in their road games this season where they will be in this game. They have won 2 of their last 3 games and are coming into this one off of a win in their last game. They just lost their 3-game series against the Los Angeles Dodgers 2-1 and they are playing the series finale of a 3-game series with the Reds on Thursday night. This will be the 3rd game of the series on Thursday with the 2nd game still to be played on Wednesday. MacKenzie Gore is the starting pitcher for them on Wednesday while Nick Martinez will be on the mound for them here on Thursday. He is 0-2 with a 4.30 ERA this season. His team lost their last 2 games this season with him as a starter. In his last start, he allowed 2 ER, 2 HRs, and 5 BB with 4 Ks on 4 hits in 4.2 IP against the Los Angeles Dodgers. They scored 6 runs in their last series averaging just over 2 runs scored per game in that span and they allowed 18 runs against them averaging 6 runs allowed per game.
Cincinnati Reds Analysis
The Reds are coming into this game with a 3-14 record overall and they are 1-5 in their home games this season where they will be in this game. They have lost 12 of their last 13 games and are coming into this one off of a loss in their last game. They just lost their 3-game series against the St. Louis Cardinals 2-1 and they are playing the series finale of a 3-game series with the Padres on Thursday night. This will be the 3rd game of the series on Thursday with the 2nd game still to be played on Wednesday. Vladimir Gutiérrez was the starter for them on Wednesday while Tyler Mahle will be throwing the first pitch for them here on Thursday. He is 1-2 with a 6.88 ERA this season. His team lost their last 3 games this season with him as a starter. In his last start, he allowed 2 ER, 0 HRs, and 3 BB with 3 Ks on 5 hits in 4.1 IP against the St. Louis Cardinals. They scored 6 runs in their last series averaging 2 runs scored per game in that span and they allowed 10 runs against them averaging just over 3 runs allowed per game.
Padres vs Reds Prediction
The Padres are coming into this game as a slight favorite with the current betting odds. They have been playing very well in their games and they have been scoring a lot of runs as that has not been a problem for them this season. They are going up against a Reds side that has had trouble hitting the ball this season and has not had any good pitching to help them out either. Martinez is starting for the Padres and he has not been great but he has not been awful either and the Padres still have the better pitching matchup here compared to the Reds. Mahle is starting for the reds and he is off to an awful start to the season as he has not had a good start yet and it will be tough for him to bounce back against a team like the Padres with how well they have been hitting recently. The best bet here is on the Padres to win as they swept the Reds just last week and they should be able to repeat that here with how bad the Reds have been.
Padres Reds Prediction: Our MLB Pick for Thursday, April 28, 2022 (12:35 pm ET start time) is Padres 8 Reds 4.
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MLB Betting Trends
San Diego Padres: 101-70 (-15.2 Units) ML as a favorite of -110 or higher. 129-117 (-28.2 Units) ML in all games. 24-18 OVER on the road when the total is 8 to 8.5.
Cincinnati Reds: TYLER MAHLE is 8-5 (+6.8 Units) ML as an underdog of +100 or higher. 25-16 OVER at home when the money line is +125 to -125. 26-18 OVER at home when the total is 7 to 8.5.
Key Injuries
San Diego Padres: L. Voit (1B) Out indefinitely - Bicep injury. M. Clevinger (SP) Early May - Knee injury. B. Snell (SP) Out indefinitely - Groin injury.
Cincinnati Reds: L. Castillo (SP) Early May - Shoulder injury. D. Duarte (RP) Out indefinitely - Elbow injury. D. Solano (2B) Early May - Hamstring injury.
Notable Quotes
"It's a great start to the road trip. Hosmer's (homer) was the big blow in that inning, but the at-bats seemed to get better as we strung them along and we just passed the baton to the next guy." - Bob Melvin after his team’s win against the Reds on Tuesday.
"We got down 9-1 and we just continued to play. We lost the game which is kind of the point, but coming back like that over the long season, those things really do matter." - David Bell after his team’s loss against the Padres on Tuesday.
Starting Lineups
San Diego Padres
Austin Nola (R) C
Jake Cronenworth (L) 2B
Manny Machado (R) 3B
Jurickson Profar (S) LF
Eric Hosmer (L) 1B
Wil Myers (R) RF
Luis Campusano (R) DH
Trent Grisham (L) CF
Ha-Seong Kim (R) SS
Cincinnati Reds
Jonathan India (R) 2B
Brandon Drury (R) DH
Tommy Pham (R) LF
Joey Votto (L) 1B
Kyle Farmer (R) SS
Nick Senzel (R) CF
Aristides Aquino (R) RF
Aramis Garcia (R) C
Matt Reynolds (R) 3B
Statistical Leaders
San Diego Padres
Batting Average: Eric Hosmer (.390)
Hits: Manny Machado (23)
Home Runs: Jurickson Profar (4)
RBI: Jurickson Profar (12)
Stolen Bases: Manny Machado (3)
Wins: Joe Musgrove (3)
Saves: Taylor Rogers (5)
ERA: Taylor Rogers (0.00)
Cincinnati Reds
Batting Average: Tyler Stephenson (.267)
Hits: Kyle Farmer (14)
Home Runs: Tyler Stephenson (2)
RBI: Kyle Farmer (7)
Stolen Bases: Kyle Farmer (1)
Wins: Hunter Greene (1)
Saves: Tony Santillan (1)
ERA: Alexis Diaz (0.00)
Managers:
San Diego Padres: Bob Melvin (1st season)
Cincinnati Reds: David Bell (4th season)