Louisville Cardinals vs Notre Dame Fighting Irish Prediction, Picks and Game Preview - 09/28/2024

by Rod Pearson

Tuesday, Sep 24, 2024
Game Time: 3:30 pm ET, Saturday, September 28, 2024
Venue:  Notre Dame Stadium, Notre Dame, IN
Where to Watch:  Peacock


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Louisville +6, Notre Dame -6; Over/Under:  48 points
Bet365:  Point Spread:  Louisville +6, Notre Dame -6; Over/Under:  48 points
BetMGM:  Point Spread:  Louisville +6, Notre Dame -6; Over/Under:  48.5 points

Season Record

Louisville Cardinals:  3-0 (1-0) (1st place, ACC)
Notre Dame Fighting Irish:  3-1 (0-0) (FBS Independent)

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Recent Form
Louisville Cardinals:  won their last game at home against the Georgia Tech Yellow Jackets 31-19.
Notre Dame Fighting Irish:  won their last game at home against the Miami-Ohio RedHawks 28-3.


Louisville Cardinals vs Notre Dame Fighting Irish Preview and Analysis


Louisville is entering this game with a 3-0 record overall and they have a 1-0 record in their conference games too. They are 3-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Georgia Tech 31-19. Tyler Shough was the starting QB and he completed 13/19 passes for 269 passing yards, 2 touchdowns, and 0 interceptions. Donald Chaney Jr. led the team in rushing yards with 23. Ja'Corey Brooks led the receivers with 125 receiving yards on 4 receptions and 1 TD. Tahveon Nicholson led the defense in that game with 7 solo tackles and 2 assisted tackles while no one on the defense recorded a sack for them. No one on the defense came away with an interception for them in that one.
 
 
 
Notre Dame is entering this game with a 3-1 record overall and they have a 0-0 record in their conference games too. They are 1-1 in their home games, 2-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Miami-Ohio 28-3. Riley Leonard was the starting QB and he completed 16/25 passes for 154 passing yards, 1 touchdown, and 0 interceptions. Riley Leonard led the team in rushing yards with 143 and 2 TDs. Beaux Collins led the receivers with 60 receiving yards on 4 receptions and 1 TD. Boubacar Traoré led the defense in that game with 4 solo tackles and 1 assisted tackle while Boubacar Traoré led the defense in sacks with 2. Junior Tuihalamaka and Christian Gray each came away with 1 interception for them in that one.


Louisville vs Notre Dame Prediction

The current betting odds have Louisville listed as a 6 point underdog in this game according to Draftkings Sportsbook. Louisville has looked really good in their games this season with their 3-0 record overall and their 1-0 conference record. They are coming off a win against GA Tech in their last one and this is still the team that went to the ACC Championship last year. Jeff Brohm did wonders in his 1st season last year and they are going to be looking to get back to the championship game again this season. Meanwhile, Notre Dame has looked good in their games this season with their 3-1 record overall, but they have looked up and down in their games. They have 2 wins against weaker opponents and a nice road win against Texas A&M, but they also have a really bad loss to Northern Illinois at home. Their offense has struggled at times while Louisville hasn't really struggled in the offensive department at all this season. Notre Dame has a really good defense that will keep them in this game if they win, but their offense isn't going to be able to roll over this Louisville defense. Louisville also has a solid offense themselves that will put up points in this one and keep the game close if they don't win outright. The best way to place a bet here is on Louisville to cover the spread in this game. 

Louisville Notre Dame Prediction:  Our NCAAF Pick for Saturday, September 28, 2024 (3:30 pm ET start time) is Louisville 23 Notre Dame 20.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Louisville Cardinals Notre Dame Fighting Irish prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.

NCAAF Betting Trends


Louisville Cardinals: 2-7 1H ATS in road lined games. 1-5 1H ATS after a 2 game home stand. 5-9 1H ATS when playing against a team with a winning record. 4-0 UNDER as an underdog of 3.5 to 10 points. 10-4 UNDER when playing against a team with a winning record. 7-2 UNDER vs. good offensive  teams - scoring 31 or more points/game.

Notre Dame Fighting Irish: 8-2 ATS against ACC opponents. 6-2 ATS as a favorite of 3.5 to 10 points. 8-3 ATS when playing against a team with a winning record. 9-4 1H UNDER in home lined games. 5-1 1H UNDER in a home game where the total is between 42.5 and 49. 8-4 1H UNDER when playing against a team with a winning record.

Key Injuries


Louisville Cardinals:  D. Chaney (RB) Questionable - Ankle. A. Williams (DB) Questionable - Undisclosed. J. Guerad (DL) Questionable - Undisclosed. J. Calloway (WR) Questionable - Undisclosed. C. Lacy (WR) Out - Collarbone.

Notre Dame Fighting Irish:  J. Burnham (DL) Out - Ankle. C. Tucker (CB) Out - Knee. G. Payne (RB) Out - Knee. C. Jagusah (OL) Out - Pectoral. T. Bennie-Powell (SAF) Out - Shoulder. S. Prescod (OL) Out - Shoulder. T. Johnson (SAF) Out - Foot.

Notable Quotes


“Took all four quarters and a lot of different things to come up and pull off the victory. We were definitely tested. It was a back-and-forth game and a lot of momentum swings, but we hung in there. Defense, while it wasn’t perfect, had some big fourth-down stops and of course a huge turnover. Special teams gave us the advantage, that was the key.” - Jeff Brohm after his team’s win against GA Tech in their last game. 


"That's part of the game, right? If you don't do your job, people are going to boo you. But if you let that affect the way you go out and execute the next play, then, man, you're not the right person for this job, or to be our quarterback at Notre Dame. So, I hope (Leonard) handled it the exact way that I would expect him to. What do you need to do to refocus, to go out the next play and get your job done?" - Marcus Freeman after his team’s win against Miami-OH in their last game. 


Starting Lineups


Louisville Cardinals
WR Brooks, Ja'Corey 
WR Bell, Chris 
WR Thompson, Jadon
TE Redman, Mark
QB Shough, Tyler
RB Turner, Maurice

Notre Dame Fighting Irish
WR Collins, Beaux 
WR Faison, Jordan 
WR Greathouse, Jaden
TE Evans, Mitchell 
QB Leonard, Riley 
RB Love, Jeremiyah 

Statistical Leaders


Louisville Cardinals
Passing: T. Shough (850)
Rushing: I. Brown (173)
Receiving: J. Brooks (297)
Touchdowns: D. Watson (2)

Notre Dame Fighting Irish
Passing: R. Leonard (587)
Rushing: J. Love (339)
Receiving: B. Collins (176)
Touchdowns: R. Leonard (6)

Coaches:
Louisville Cardinals: Jeff Brohm (2nd season)
Notre Dame Fighting Irish: Marcus Freeman (4th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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