Los Angeles Rams vs San Francisco 49ers Prediction, Preview and Odds - 12/12/2024

by Rod Pearson

Monday, Dec 09, 2024
Game Time: 8:15 pm ET, Thursday, December 12, 2024
Venue:  Levi's Stadium, Santa Clara, CA
Where to Watch:  Amazon Prime Video


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Rams +2, 49ers -2; Over/Under:  48.5 points
Bet365:  Point Spread:  Rams +2, 49ers -2; Over/Under:  48.5 points
BetMGM:  Point Spread:  Rams +2, 49ers -2; Over/Under:  48.5 points

Season Record

Los Angeles Rams:  7-6 (2nd place, NFC West)
San Francisco 49ers:  6-7 (4th place, NFC West)

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Recent Form
Los Angeles Rams:  won their last game at home against the Buffalo Bills 44-42.
San Francisco 49ers:  won their last game at home against the Chicago Bears 38-13.


Los Angeles Rams vs San Francisco 49ers Preview and Analysis


The Rams are entering this game with a 7-6 record overall and they have a 2-1 record in their divisional games too. They are 4-3 in their home games, 3-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Buffalo Bills 44-42. Matthew Stafford was the starting QB and he completed 23/30 passes for 320 passing yards, 2 touchdowns, and 0 interceptions. Kyren Williams led the team in rushing yards with 87 and 2 TDs. Puka Nacua led the receivers with 162 receiving yards on 12 receptions and 1 TD. Darious Williams led the defense in that game with 5 solo tackles and 1 assisted tackle while no one on the defense recorded a sack for them. No one on the defense came away with an interception for them in that one.
 
 
 
The 49ers are entering this game with a 6-7 record overall and they have a 1-3 record in their divisional games too. They are 4-3 in their home games, 2-4 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Chicago Bears 38-13. Brock Purdy was the starting QB and he completed 20/25 passes for 325 passing yards, 2 touchdowns, and 0 interceptions. Isaac Guerendo led the team in rushing yards with 78 and 2 TDs. George Kittle led the receivers with 151 receiving yards on 6 receptions. De'Vondre Campbell Sr. led the defense in that game with 6 solo tackles and 1 assisted tackle while Yetur Gross-Matos led the defense in sacks with 3. No one on the defense came away with an interception for them in that one.


Rams vs 49ers Prediction

The current betting odds have the Rams listed as a 2 point underdog in this game according to Draftkings Sportsbook. The Rams have looked good in their games this season with their 7-6 record overall which has them in 2nd place of the NFC West and fighting for the division. They are coming off a huge win against the Bills in their last one and that game is not only going to give them momentum going forward, but it was also a huge game for them to win to get back in the division race. The Rams are now in control of their destiny and this is another big game for them to not only stay in this NFC West race, but also put their opponent down and out of it. Meanwhile, the 49ers haven't looked great in their games this season with their 6-7 record overall which has them at the bottom of the NFC West. They may be at the bottom of the division, but they are coming off a big win over the Bears in their last one and have now given themselves a chance to get back in the division race. This is another game they have to win though, but they just haven't looked like the same team that was in the Super Bowl just a season ago. They have been limping with injuries and inconsistent play each week while the Rams have been getting hot lately, looking a lot better with their playmakers healthy now. Their offense has also looked a lot better while the 49ers have been really up and down from week to week. This is a game that both teams need to win for the division race, but the Rams are playing a lot better at the moment. The best way to place a bet here is on the Rams to cover the spread in this game. 

Rams 49ers Prediction:  Our NFL Pick for Thursday, December 12, 2024 (8:15 pm ET start time) is Rams 31 49ers 27.
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NFL Betting Trends


Los Angeles Rams: 8-3 ATS in a road game where the total is between 42.5 and 49 points. 9-5 ATS versus division opponents. 5-2 ATS after scoring 30 points or more last game. 8-4 UNDER as a road underdog of 7 points or less. 6-2 UNDER after allowing 30 points or more last game. 7-2 UNDER vs. good passing teams averaging 235 or more passing yards/game.

San Francisco 49ers: 3-8 ATS in a home game where the total is greater than or equal to 45.5. 4-11 ATS vs. good passing teams averaging 7 or more passing yards/att. 7-16 ATS versus good offensive teams - averaging 5.65 yards/play or more. 4-1 UNDER revenging a road loss against an opponent. 9-5 UNDER vs. bad defensive teams who give up 24 or more points/game.

Key Injuries


Los Angeles Rams:  R. Havenstein (OL) Injured - Rest. J. Verse (OLB) Questionable - Ankle. M. Stafford (QB) Injured - Ankle. D. Robinson (WR) Injured - Hand. C. Kupp (WR) Injured - Rest. T. Davis (DL) Injured - Ankle. T. Higbee (TE) Out - Knee. A. Jackson (OL) Questionable - Foot. K. Leveston (OL) Out - Ankle.

San Francisco 49ers:  C. Ward (CB) Injured - Rest. G. Odum (SAF) Out - Knee. Y. Gross-Matos (DL) Injured - Knee. T. Hufanga (SAF) Questionable - Wrist. J. Mason (RB) Out - Ankle. S. Okuayinonu (DL) Injured - Wrist. T. Williams (OT) Out - Ankle. D. Greenlaw (LB) Out - Achilles. D. Flannigan-Fowles (LB) Questionable - Knee. J. Elliott (DL) Injured - Concussion. N. Bosa (DL) Doubtful - Hip. D. Lenoir (DB) Injured - Knee. A. Banks (OL) Questionable - Concussion. B. Purdy (QB) Injured - Shoulder. D. Puni (OL) Injured - Shoulder.

Notable Quotes


“Josh Allen is an alien. Some of the stuff that he can do and the things that he can create, we knew he was capable of that. He’s shown that. That’s why he’s as well-respected and well-regarded in this league as he is. But our guys made just enough plays to be able to come out on top.” - Sean McVay after his team’s win against the Bills in their last game. 


“The message was we need to play with more of a sense of urgency and play desperate. Because you just hadn't really sensed that.” - George Kittle after their win against the Bears in their last game. 


Starting Lineups


Los Angeles Rams
WR Robinson, Demarcus 
WR Nacua, Puka
WR Kupp, Cooper
TE Allen, Davis 
QB Stafford, Matthew 
RB Williams, Kyren

San Francisco 49ers
WR Pearsall, Ricky
WR Samuel Sr., Deebo
WR Jennings, Jauan
TE Kittle, George 
QB Purdy, Brock 
RB Guerendo, Isaac 
FB Juszczyk, Kyle

Statistical Leaders


Los Angeles Rams
Passing: M. Stafford (3303)
Rushing: K. Williams (1013)
Receiving: P. Nacua (708)
Touchdowns: K. Williams (14)

San Francisco 49ers
Passing: B. Purdy (3032)
Rushing: J. Mason (789)
Receiving: G. Kittle (800)
Touchdowns: G. Kittle (8)

Coaches:
Los Angeles Rams: Sean McVay (8th season)
San Francisco 49ers: Kyle Shanahan (8th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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