Arizona Wildcats vs Duke Blue Devils Prediction, Picks and Game Preview - 03/27/2025

Game Time: 9:39 pm ET, Thursday, March 27, 2025

Venue:  Prudential Center, Newark, NJ

Where to Watch:  CBS

DraftKings:  Point Spread:  Arizona +8.5, Duke -8.5; Over/Under:  153.5 points

Bet365:  Point Spread:  Arizona +8.5, Duke -8.5; Over/Under:  153.5 points

BetMGM:  Point Spread:  Arizona +8.5, Duke -8.5; Over/Under:  153.5 points

Arizona Wildcats:  24-12 (14-6) (3rd place, Big 12)

Duke Blue Devils:  33-3 (19-1) (1st place, ACC)

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Arizona Wildcats:  4-1  last 5

Duke Blue Devils:  5-0  last 5

Arizona is entering this game with a 24-12 record overall, a 14-6 record in conference games, and they are 5-4 in their neutral site games this season where they will be in this game. They are coming off a win against the Oregon Ducks in their last game. Caleb Love led the team in points in that game with 29 while Tobe Awaka, Jaden Bradley, Anthony Dell'Orso, and KJ Lewis each were next on the team with 12. Jaden Bradley and Caleb Love each led the team in assists with 4 in that game while Tobe Awaka led the team in rebounds with 14. They were 45.5% from the field, 50% from 3-point range, and 70.8% from the free throw line with their shooting in that game. Their offense is averaging 82.2 PPG and their defense is allowing their opponents to average 72.5 PPG against them. Arizona has an ATS record of 19-17 this season and their O/U record is 20-16.

Duke is entering this game with a 33-3 record overall, a 19-1 conference record, and they are 6-2 in their neutral site games this season where they will be in this game. They are coming off a win against the Baylor Bears in their last game. Tyrese Proctor led the team in points in that game with 25 while Cooper Flagg was next on the team with 18. Cooper Flagg led the team in assists with 6 in that game while Cooper Flagg led the team in rebounds with 9. They were 64.4% from the field, 54.5% from 3-point range, and 82.6% from the free throw line with their shooting in that game. Their offense is averaging 83.2 PPG and their defense is allowing their opponents to average 61.7 PPG against them. Duke has an ATS record of 24-12 this season and their O/U record is 19-17.

The current betting odds have Duke listed as an 8.5 point favorite in this game according to Draftkings Sportsbook. Duke has looked great in their games this season with their 33-3 record overall and their 19-1 conference record which had them right at the top of the ACC. They have looked good in their neutral site games too as they are 6-2 in those. Meanwhile, Arizona has looked good in their games this season with their 24-12 record overall and their 14-6 conference record which had them in the top half of the Big 12. They haven't looked as good in neutral site games though, going 5-4 in those. They have looked a lot better lately as they finished the season hot and they have been great in this tournament too. They blew out Akron by almost 30 points in their 1st game and are now coming off a win over Oregon, but that was a much tighter game for them. They got down by double digits early and fought back to take the lead by halftime, even pulling away in the 2nd half, but they only won by 4 points in the end as they started to blow their lead near the end. Duke has also been rolling lately, but they have been blowing out almost every opponent they see. They had a huge win over Mount St Mary's in the 1st round and now they are coming off a win over Baylor in their last game by over 20 points. Arizona has looked good lately, but they have struggled a lot this season when they have had to play better teams, and Duke has been one of the best teams in the nation all year with a ton of talent both offensively and defensively. The best way to place a bet here is on Duke to cover the spread in this game. 

Arizona Duke Prediction:  Our NCAAB Pick for Thursday, March 27, 2025 (9:39 pm ET start time) is Duke 88 Arizona 68.

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Arizona Wildcats: 8-14 ATS on the road or at a neutral site versus good rebounding teams - outrebounding opponents by 4+ per game. 7-12 ATS on the road or at a neutral site versus excellent teams - shooting 45% or more with a defense of 42% or less. 8-4 UNDER as an underdog. 5-1 UNDER in NCAA tournament games.

Duke Blue Devils: 19-8 ATS after scoring 85 points or more. 22-14 ATS versus very good teams - outscoring their opponents by 8+ points/game. 26-17 ATS versus good defensive teams - shooting pct defense of 42% or less. 18-7 UNDER in all neutral court games. 15-8 UNDER in all tournament games. 19-10 UNDER versus good rebounding teams - outrebounding opponents by 4+ per game.

Arizona Wildcats:  M. Krivas (C) Out - Lower Leg.

Duke Blue Devils:  M. Brown (F) Questionable - Shoulder.

“We’ve really been talking about this, kind of developing — I don’t want to say unemotional, but a real steady approach. Zero-zero score, so what, now what mentality. They executed it to perfection today.” - Tommy Lloyd after his team’s win against Oregon in the 2nd round of the NCAA Tournament. 

“For us to win by this margin, I think this speaks to the level of killer instinct that our guys have, the competitiveness and the connectivity.” - Jon Scheyer after his team’s win against Baylor in the 2nd round of the NCAA Tournament.

T. Awaka 

J. Bradley 

A. Dell'Orso 

C. Love 

T. Townsend

C. Flagg 

S. James 

K. Knueppel 

K. Maluach 

T. Proctor

PPG: C. Love (16.4)

APG: J. Bradley (3.8)

Reb/G: T. Awaka (8)

PPG: C. Flagg (18.9)

APG: C. Flagg (4.1)

Reb/G: C. Flagg (7.5)

Coaches:

Arizona Wildcats: Tommy Lloyd (4th season)

Duke Blue Devils: Jon Scheyer (3rd season)