Arizona Cardinals vs Carolina Panthers Prediction, Preview and Odds - 12/22/2024

by Rod Pearson

Wednesday, Dec 18, 2024
Game Time: 1:00 pm ET, Sunday, December 22, 2024
Venue:  Bank of America Stadium, Charlotte, NC
Where to Watch:  FOX


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Cardinals -4.5, Panthers +4.5; Over/Under:  47 points
Bet365:  Point Spread:  Cardinals -4.5, Panthers +4.5; Over/Under:  47 points
BetMGM:  Point Spread:  Cardinals -4, Panthers +4; Over/Under:  47 points

Season Record

Arizona Cardinals:  7-7 (3rd place, NFC West)
Carolina Panthers:  3-11 (4th place, NFC South)

Do not miss out on our expert handicapper analysis! Vegas Writer is on a HOT STREAK in the NFL on a 23-13-1 NFL RUN for +$8,620 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Recent Form
Arizona Cardinals:  won their last game at home against the New England Patriots 30-17.
Carolina Panthers:  lost their last game at home against the Dallas Cowboys 30-14.


Arizona Cardinals vs Carolina Panthers Preview and Analysis


The Cardinals are entering this game with a 7-7 record overall and they have a 2-2 record in their divisional games too. They are 5-3 in their home games, 2-4 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the New England Patriots 30-17. Kyler Murray was the starting QB and he completed 23/30 passes for 224 passing yards, 0 touchdowns, and 0 interceptions. James Conner led the team in rushing yards with 110 and 2 TDs. Trey McBride led the receivers with 87 receiving yards on 9 receptions. Budda Baker led the defense in that game with 7 solo tackles and 3 assisted tackles while Baron Browning and Darius Robinson each led the defense in sacks with 1. Sean Murphy-Bunting came away with the only interception for them in that one.
 
 
 
The Panthers are entering this game with a 3-11 record overall and they have a 1-3 record in their divisional games too. They are 1-6 in their home games, 1-5 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Dallas Cowboys 30-14. Bryce Young was the starting QB and he completed 19/28 passes for 219 passing yards, 1 touchdown, and 2 interceptions. Chuba Hubbard led the team in rushing yards with 32. Jalen Coker led the receivers with 110 receiving yards on 4 receptions and 1 TD. Josey Jewell led the defense in that game with 5 solo tackles and 5 assisted tackles while Jaycee Horn led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.


Cardinals vs Panthers Prediction

The current betting odds have the Cardinals listed as a 4.5 point favorite in this game according to Draftkings Sportsbook. The Cardinals haven't looked great in their games this season with their 7-7 record overall which has them in 3rd place of the NFC West, but that record still has them in the playoff race with something to fight for. They looked terrible in their games coming out of their bye week, but they finally got a win over the Patriots last week and they have been beating up on bad opponents all season. Meanwhile, the Panthers have looked terrible in their games this season with their 3-11 record overall which has them at the bottom of the NFC South with one of the worst records in the entire NFL. They have already been eliminated from playoff contention and really have nothing left to play for this season. They were starting to look good over the last month as they had some tight games against better teams like the Chiefs and the Eagles, almost winning both of those games, but they finally ran out of gas last week as the Cowboys came into town and had complete control in that 30-14 loss for the Panthers. Bryce Young has looked better lately, but that loss is going to deflate them a bit after 3 good performances. The Cardinals are also going to have some momentum now that they finally broke their losing streak and they are still fighting for a playoff spot but can't afford to lose another game. The Cardinals have been in complete control against bad opponents this season and this is a game they need to win against one of the worst in the NFL at the moment. The best way to place a bet here is on the Cardinals to cover the spread in this game. 

Cardinals Panthers Prediction:  Our NFL Pick for Sunday, December 22, 2024 (1:00 pm ET start time) is Cardinals 28 Panthers 16.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Arizona Cardinals Carolina Panthers prediction, be sure to drop by every day for our weekly NFL predictions and previews.

NFL Betting Trends


Arizona Cardinals: 5-0 ATS against NFC South division opponents. 23-16 ATS when playing with 6 or less days rest. 7-3 UNDER in games played on turf. 7-3 1H UNDER versus poor defensive teams - allowing 350 yards/game or more.

Carolina Panthers: 19-27 ATS in all games. 1-4 ATS against NFC West division opponents. 4-11 ATS after allowing 30 points or more last game. 11-5 UNDER after a loss by 14 or more points. 8-4 UNDER after a game with a turnover margin of -2 or worse. 

Key Injuries


Arizona Cardinals:  K. Murray (QB) Injured - Illness. R. Lopez (DL) Questionable - Ankle. B. Gillikin (P) Out - Foot. E. Demercado (RB) Out - Back. T. McBride (TE) Injured - Knee. N. Jones (DT) Questionable - Shoulder. E. Jones (CB) Out - Ankle. K. Beachum (OL) Injured - NIR-Rest. D. Robinson (DL) Injured - Calf.

Carolina Panthers:  J. Horn (CB) Questionable - Groin. T. Wallace (LB) Out - Shoulder. L. Johnson (SAF) Injured - Neck. R. Blackshear (RB) Questionable - Chest. N. Scott (SAF) Questionable - Hamstring. C. Farley (CB) Injured - Shoulder. J. Jewell (LB) Questionable - Hamstring. J. Coker (WR) Injured - Quadriceps. D. Wonnum (OLB) Injured - Knee. J. Clowney (OLB) Questionable - Knee. T. Moton (T) Injured - NIR - Rest. A. Robinson (DE) Injured - NIR - Rest. C. Hubbard (RB) Injured - NIR - Rest.

Notable Quotes


“It's a cool thing for me — roles change like that in the ballgame, but they step up and play good football for us. We've got a lot of versatile guys who can play.” - Jonathan Gannon after his team’s win against the Patriots in their last game. 


“When they put us in this mode where we have to play behind, where we have to throw the ball and flip the field to score some points, we were playing into their hands. Certainly put us in a brand of football that we don’t really want to play.” - Dave Canales after his team’s loss against the Cowboys in their last game. 


Starting Lineups


Arizona Cardinals
WR Jones, Zay
WR Harrison Jr., Marvin
WR Wilson, Michael 
TE McBride, Trey
QB Murray, Kyler 
RB Conner, James 

Carolina Panthers
WR Coker, Jalen 
WR Moore, David   
WR Thielen, Adam
TE Tremble, Tommy  
QB Young, Bryce 
RB Hubbard, Chuba 

Statistical Leaders


Arizona Cardinals
Passing: K. Murray (3086)
Rushing: J. Conner (973)
Receiving: T. McBride (938)
Touchdowns: J. Conner (8)

Carolina Panthers
Passing: B. Young (1791)
Rushing: C. Hubbard (1043)
Receiving: X. Legette (439)
Touchdowns: C. Hubbard (9)

Coaches:
Arizona Cardinals: Jonathan Gannon (2nd season)
Carolina Panthers: Dave Canales (1st season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

© 2024 Al McMordie's BigAl.com. All Rights Reserved.