Denver Broncos vs Buffalo Bills Prediction, Preview and Odds - 01/12/2025

Game Time: 1:00 pm ET, Sunday, January 12, 2025

Venue:  Highmark Stadium, Orchard Park, NY 

Where to Watch:  CBS

DraftKings:  Point Spread:  Broncos +8.5, Bills -8.5; Over/Under:  47.5 points

Bet365:  Point Spread:  Broncos +8.5, Bills -8.5; Over/Under:  47 points

BetMGM:  Point Spread:  Broncos +9, Bills -9; Over/Under:  47.5 points

Denver Broncos:  10-7 (3rd place, AFC West)

Buffalo Bills:  13-4 (1st place, AFC East)

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Denver Broncos:  won their last game at home against the Kansas City Chiefs 38-0.

Buffalo Bills:  lost their last game on the road against the New England Patriots 23-16.

The Broncos finished the NFL regular season with a 10-7 record overall and they were 3-3 in their divisional games. They were 6-2 in their home games, 4-5 in their road games, and they were also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Kansas City Chiefs 38-0. Bo Nix was the starting QB and he completed 26/29 passes for 321 passing yards, 4 touchdowns, and 0 interceptions. Bo Nix led the team in rushing yards with 47. Courtland Sutton led the receivers with 98 receiving yards on 5 receptions and 1 TD. Nik Bonitto, Ja'Quan McMillian, and Patrick Surtain II each led the defense in that game with 3 solo tackles and 0 assisted tackles while Nik Bonitto led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

 

 

 

The Bills finished the NFL regular season with a 13-4 record overall and they were 5-1 in their divisional games. They were 8-0 in their home games, 5-4 in their road games, and they were also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the New England Patriots 23-16. Josh Allen was the starting QB but left after 1 play while Mitchell Trubisky came in and he completed 15/21 passes for 101 passing yards, 1 touchdown, and 0 interceptions. Ray Davis led the team in rushing yards with 64. Curtis Samuel led the receivers with 52 receiving yards on 7 receptions. Javon Solomon led the defense in that game with 4 solo tackles and 3 assisted tackles while Von Miller led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have the Bills listed as an 8.5 point favorite in this game according to Draftkings Sportsbook. The Bills have looked really good in their games this season with their 13-4 record overall which leads the AFC East with one of the best records in the NFL. They are the 2nd seed in the AFC with that record and even though they are coming off a 23-16 loss to the Patriots last week, that was a game that they rested most of their starters in and used it as a bye week. Meanwhile, the Broncos have looked good in their games this season with their 10-7 record overall, but that record has them in 3rd place of the AFC West and in the Wild Card as the 7th and last seed in the AFC. They are coming off a nice 38-0 win over the Chiefs last week which they needed to clinch their playoff spot, but the Broncos have been in control of their own destiny over the last month, needing just 1 win to clinch, and it took them right until week 18 with the Chiefs resting all of their starters just to get to the playoffs. The Broncos have had a great defense all season and Bo Nix has looked really good in his rookie year, but they haven't looked that good over the last month. Their defense hasn't looked as good against better offenses this season either, and now they have to go on the road here to face one of the best offenses in the NFL who used last week to rest players for this game. This has been a great season for the Broncos, but this is where their story ends as the Bills have looked like one of the best teams in the NFL all season. The best way to place a bet here is on the Bills to cover the spread in this game. 

Broncos Bills Prediction:  Our NFL Pick for Sunday, January 12, 2025 (1:00 pm ET start time) is Bills 34 Broncos 17.

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Denver Broncos: 10-3 ATS as an underdog of 3.5 to 9.5 points. 5-1 ATS when playing against a top-level team (Win Pct. > 75%). 6-1 ATS vs. good teams - outscoring opponents by 6+ PPG on the season. 8-4 OVER off a home win. 6-0 OVER after scoring 30 points or more last game. 6-3 OVER after a win by 14 or more points.

Buffalo Bills: 1-3 ATS in playoff games. 2-6 1H ATS in January games. 12-6 OVER after playing a division game. 28-18 1H OVER as a favorite. 18-8 1H OVER in home games. 5-0 1H OVER off an upset loss as a road favorite.

Denver Broncos:  T. Badie (RB) Questionable - Back. T. Franklin (WR) Injured - Ankle. J. McLaughlin (RB) Injured - Quad. R. Moss (CB) Injured - Knee.

Buffalo Bills:  T. Grable (OT) Injured - NIR-Personal. S. Martin (P) Injured - Back. D. Smoot (DE) Injured - Wrist. M. Milano (LB) Injured - Biceps. J. Phillips (DT) Injured - Back. C. Samuel (WR) Questionable - Rib. R. Douglas (CB) Injured - Knee. J. Allen (QB) Injured - Elbow. C. Lewis (DB) Questionable - Shoulder. Q. Morris (TE) Injured - Shoulder. D. Hamlin (SAF) Questionable - Rib. T. Rapp (SAF) Questionable - Neck. D. Williams (LB) Injured - Elbow. D. Kincaid (TE) Injured - Knee. S. Brown (T) Injured - Neck. D. Carter (DT) Injured - Wrist.

“I learned I’ve got to run a little more during the week because that’s a long lap. I was a little tired at the end. But the fans deserve it, it’s been a long time coming.” - Bo Nix after their win against the Chiefs in their regular season finale.

“Everything is earned and there’s nothing given in the playoffs. And you’re going against the best every week, so we start with one week and really one day at a time and get back in here and find out when we play and take it one day at a time.” - Sean McDermott after his team’s loss against the Patriots in their regular season finale. 

WR Sutton, Courtland 

WR Mims Jr., Marvin

WR Vele, Devaughn

TE Trautman, Adam

QB Nix, Bo

RB Estime, Audric

FB Burton, Michael

WR Coleman, Keon

WR Hollins, Mack 

WR Shakir, Khalil 

TE Knox, Dawson

QB Allen, Josh 

RB Cook, James 

FB Gilliam, Reggie

Passing: B. Nix (3775)

Rushing: J. Williams (513)

Receiving: C. Sutton (1081)

Touchdowns: C. Sutton (8)

Passing: J. Allen (3731)

Rushing: J. Cook (981)

Receiving: K. Shakir (821)

Touchdowns: J. Cook (17)

Coaches:

Denver Broncos: Sean Payton (2nd season)

Buffalo Bills: Sean McDermott (8th season)