by Rod Pearson
Monday, Jan 22, 2024
Game Time: 6:30 pm ET, Sunday, January 28, 2024
Venue: Levi's Stadium, Santa Clara, CA
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Lions +6.5, 49ers -6.5; Over/Under: 51 points
Bet365: Point Spread: Lions +7, 49ers -7; Over/Under: 51 points
BetMGM: Point Spread: Lions +6.5, 49ers -6.5; Over/Under: 51 points
Season Record
Detroit Lions: 12-5 (1st place, NFC North)
San Francisco 49ers: 12-5 (1st place, NFC West)
Do not miss out on our expert handicapper analysis! Matt Fargo is on a HOT STREAK in the NFL on a 16-7 NFL RUN for +$8,170 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.
Recent Form
Detroit Lions: won their last game at home against the Tampa Bay Buccaneers 31-23.
San Francisco 49ers: won their last game at home against the Green Bay Packers 24-21.
Detroit Lions vs San Francisco 49ers Preview and Analysis
The Lions are entering this game with a 12-5 record overall and they have a 4-2 record in their divisional games too. They are 6-2 in their home games, 6-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Tampa Bay Buccaneers 31-23 in the NFC Divisional Round of the NFL playoffs. Jared Goff was the starting QB and he completed 30/43 passes for 287 passing yards, 2 touchdowns, and 0 interceptions. Jahmyr Gibbs led the team in rushing yards with 74 and 1 TD. Amon-Ra St. Brown led the receivers with 77 receiving yards on 8 receptions and 1 TD. Brian Branch led the defense in that game with 8 solo tackles and 1 assisted tackle while Ifeatu Melifonwu led the defense in sacks with 1.5. Derrick Barnes and C. J. Gardner-Johnson each came away with 1 interception for them in that game.
The 49ers are entering this game with a 12-5 record overall and they have a 5-1 record in their divisional games too. They are 5-3 in their home games, 7-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Green Bay Packers 24-21 in the NFC Divisional Round of the NFL playoffs. Brock Purdy was the starting QB and he completed 23/39 passes for 252 passing yards, 1 touchdown, and 0 interceptions. Christian McCaffrey led the team in rushing yards with 98 and 2 TDs. George Kittle led the receivers with 81 receiving yards on 4 receptions and 1 TD. Dre Greenlaw led the defense in that game with 6 solo tackles and 2 assisted tackles while no one on the defense recorded a sack in that one. Dre Greenlaw came away with the only 2 interceptions for them in that game.
Lions vs 49ers Prediction
The current betting odds have the Lions listed as a 6.5 point underdog in this game according to Draftkings Sportsbook. The Lions have looked great in their games this season with their 12-5 record overall which won the NFC North for them for the 1st time in years. They also have a ton of momentum on their side right now as they hadn't won a playoff game in over 30 years and now have 2 playoff wins at home this year. Dan Campbell has turned this team around in a short period of time and even though they have to go on the road for this game, they were still 6-3 in their road games this season. Meanwhile, the 49ers have also looked great in their games this season with their 12-5 record overall which won the NFC West and the number 1 seed in the NFC. They have looked like one of the best teams in the NFL all season with the talent they have and some of the scores they have won their games by, but they have actually been worse at home this season with their 5-3 home record. They also didn't look great in their last game against the Packers as they struggled to win that game at home against the lowest seed in the playoffs on either side, even needing a last-minute game-winning drive just to win. The 49ers still have one of the best teams in the NFL with the talent on that offense along with one of the best defenses in the NFL, but the Lions have been rolling with a lot of momentum right now and they can keep this game close enough if they don't pull of an upset win. The best way to place a bet here is on the Lions to cover the spread in this game.
Lions 49ers Prediction: Our NFL Pick for Sunday, January 28, 2024 (6:30 pm ET start time) is 49ers 31 Lions 28.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Detroit Lions San Francisco 49ers prediction, be sure to drop by every day for our weekly NFL predictions and previews.
NFL Betting Trends
Detroit Lions: 36-17 ATS in all games. 22-10 ATS as an underdog. 11-3 ATS off a home win. 12-7 OVER in all games. 23-15 OVER against conference opponents. 6-1 OVER after a 2 game home stand. 8-4 OVER after 1 or more consecutive wins against the spread.
San Francisco 49ers: 2-5 ATS as a favorite of 3.5 to 9.5 points. 3-6 ATS in home games. 4-10 ATS in a home game where the total is greater than or equal to 49.5. 10-1 OVER as a home favorite of 3.5 to 7 points. 6-1 OVER off 1 or more consecutive unders. 12-6 OVER off a home win.
Key Injuries
Detroit Lions: K. Raymond (WR) Ques Jan 28 - Knee. J. Jackson (G) Ques Jan 28 - Knee. J. Jacobs (CB) I-R - Thigh. J. Mitchell (TE) I-R - Hand. H. Vaitai (G) Out indefinitely - Back. S. Daly (LS) Out indefinitely - Knee. E. Moseley (CB) I-R - Knee. Z. Knight (RB) I-R - Shoulder. M. Nelson (OT) Out indefinitely - Ankle. N. Sudfeld (QB) I-R - Knee. S. Zylstra (TE) I-R - Knee.
San Francisco 49ers: D. Samuel (WR) Ques Jan 28 - Shoulder. C. Ferrell (DL) I-R - Knee. D. Gray (WR) I-R - Shoulder. R. Dwelley (TE) I-R - Ankle. K. Davis (DL) Out indefinitely - Ankle. T. Hufanga (S) I-R - Knee. N. Zakelj (OL) I-R - Bicep. D. Jackson (DL) Out indefinitely - Knee. C. Latu (TE) I-R - Knee.
Notable Quotes
“I envisioned that we would have a chance to compete with the big boys, and that’s where we’re at.” - Dan Campbell after his team’s win against the Bucs in their last game.
“It was the story of our whole team. There were times when we were all off.” - Kyle Shanahan after his team’s win against the Packers in their last game.
Starting Lineups
Detroit Lions
WR Williams, Jameson
WR Reynolds, Josh
WR St. Brown, Amon-Ra
TE LaPorta, Sam
QB Goff, Jared
RB Gibbs, Jahmyr
FB Cabinda, Jason
San Francisco 49ers
WR Aiyuk, Brandon
WR Samuel, Deebo
WR Jennings, Jauan
TE Kittle, George
QB Purdy, Brock
RB McCaffrey, Christian
FB Juszczyk, Kyle
Statistical Leaders
Detroit Lions
Passing: J. Goff (4575)
Rushing: D. Montgomery (1015)
Receiving: A. St. Brown (1515)
Touchdowns: D. Montgomery (13)
San Francisco 49ers
Passing: J. Love (4159)
Rushing: A. Jones (656)
Receiving: J. Reed (793)
Touchdowns: J. Reed (10)
Coaches:
Detroit Lions: Dan Campbell (3rd season)
San Francisco 49ers: Kyle Shanahan (7th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
